BDBM50087002 1-Phenyl-8-(1,2,3,4-tetrahydro-naphthalen-1-yl)-1,3,8-triaza-spiro[4.5]decan-4-one::CHEMBL27716

SMILES O=C1NCN(c2ccccc2)C11CCN(CC1)[C@@H]1CCCc2ccccc12

InChI Key InChIKey=NKJVDKFKDYMREK-OAQYLSRUSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50087002   

TargetNociceptin receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087002(1-Phenyl-8-(1,2,3,4-tetrahydro-naphthalen-1-yl)-1,...)
Affinity DataKi:  2.5nMAssay Description:Competitive binding affinity against transfected HEK293 cells expressing Opioid receptor like 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087002(1-Phenyl-8-(1,2,3,4-tetrahydro-naphthalen-1-yl)-1,...)
Affinity DataKi:  12nMAssay Description:Competitive binding displacement analyses was performed from permanently transfected HEK293 cells expressing Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087002(1-Phenyl-8-(1,2,3,4-tetrahydro-naphthalen-1-yl)-1,...)
Affinity DataKi:  46nMAssay Description:Competitive binding displacement analyses was performed from permanently transfected HEK293 cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50087002(1-Phenyl-8-(1,2,3,4-tetrahydro-naphthalen-1-yl)-1,...)
Affinity DataKi:  530nMAssay Description:Competitive binding displacement analyses was performed from permanently transfected HEK293 cells expressing Opioid receptor delta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed