BDBM50087132 CHEMBL3426623

SMILES COC(=O)Cc1cccc(NC(=O)c2cccc(c2)-c2cc(ccc2CN)C(=O)Nc2ccncc2F)c1

InChI Key InChIKey=AQCRFIIWEURQID-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50087132   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Agoralaan Abis

Curated by ChEMBL
LigandPNGBDBM50087132(CHEMBL3426623)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Agoralaan Abis

Curated by ChEMBL
LigandPNGBDBM50087132(CHEMBL3426623)
Affinity DataIC50:  144nMAssay Description:Inhibition of human N-terminal GST-tagged ROCK2 expressed in baculovirus-infected insect cells using long S6 kinase peptide as substrate by radiometr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Agoralaan Abis

Curated by ChEMBL
LigandPNGBDBM50087132(CHEMBL3426623)
Affinity DataIC50: <1nMAssay Description:Inhibition of human N-terminal GST-tagged ROCK1 expressed in insect cells using long S6 kinase peptide as substrate by radiometric assay in presence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed