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BDBM50087864 CHEMBL3426909

SMILES: CCCCC(Oc1cc(O)c(cc1C#CC1CCCC1)C(O)=O)C(=O)NC1CCCCCCC1

InChI Key: InChIKey=FOEBFYZERNEXBZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50087864   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear proteasome inhibitor UBLCP1


(Homo sapiens (Human))
BDBM50087864
PNG
(CHEMBL3426909)
Show SMILES CCCCC(Oc1cc(O)c(cc1C#CC1CCCC1)C(O)=O)C(=O)NC1CCCCCCC1
Show InChI InChI=1S/C28H39NO5/c1-2-3-15-25(27(31)29-22-13-7-5-4-6-8-14-22)34-26-19-24(30)23(28(32)33)18-21(26)17-16-20-11-9-10-12-20/h18-20,22,25,30H,2-15H2,1H3,(H,29,31)(H,32,33)
UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.20E+3n/an/an/an/a6.0n/a



Indiana University

Curated by ChEMBL


Assay Description
Inhibition of His6-tagged UBLCP1 (unknown origin) expressed in Escherichia coli BL21 cells using pNPP as substrate at pH 6 at 25 degC by spectrophoto...


Bioorg Med Chem 23: 2798-809 (2015)


Article DOI: 10.1016/j.bmc.2015.03.066
BindingDB Entry DOI: 10.7270/Q2VD7168
More data for this
Ligand-Target Pair