BDBM50088347 1,4-Bis-[3-(3,4-dihydroxy-phenyl)-acryloyloxy]-3,5-dihydroxy-cyclohexanecarboxylic acid::CHEMBL67233::cid_14446

SMILES OC1CC(CC(O)C1OC(=O)\C=C/c1ccc(O)c(O)c1)(OC(=O)\C=C/c1ccc(O)c(O)c1)C(O)=O

InChI Key InChIKey=IYXQRCXQQWUFQV-VHOZIDCHSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50088347   

TargetM18 aspartyl aminopeptidase(Plasmodium falciparum 3D7)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50088347(1,4-Bis-[3-(3,4-dihydroxy-phenyl)-acryloyloxy]-3,5...)
Affinity DataIC50:  1.95E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088347(1,4-Bis-[3-(3,4-dihydroxy-phenyl)-acryloyloxy]-3,5...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of HIV-1 integrase, under 1 uM for the 3''-preprocessingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrase(Human immunodeficiency virus 1)
University Of California

Curated by ChEMBL
LigandPNGBDBM50088347(1,4-Bis-[3-(3,4-dihydroxy-phenyl)-acryloyloxy]-3,5...)
Affinity DataIC50:  7.80E+3nMAssay Description:Tested for inhibition of HIV-1 integrase, under 1 uM for the strand transferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50088347(1,4-Bis-[3-(3,4-dihydroxy-phenyl)-acryloyloxy]-3,5...)
Affinity DataIC50: >5.96E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay