BDBM50088858 CHEMBL3577566

SMILES COc1cccc(c1)N1C(=O)\C(=C\c2ccc(OCC(=O)Nc3ccc(C)cc3)cc2)N=C1c1ccccc1

InChI Key InChIKey=SEMPYBYEGODUIH-CEUNXORHSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50088858   

TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50088858(CHEMBL3577566)
Affinity DataIC50:  25nMAssay Description:Inhibition of ERK1 (unknown origin) using GFP-ATF2 as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50088858(CHEMBL3577566)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of ERK2 (unknown origin) using GFP-ATF2 as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Cairo University

Curated by ChEMBL
LigandPNGBDBM50088858(CHEMBL3577566)
Affinity DataIC50:  4.5nMAssay Description:Inhibition of p38alpha MAP kinase (unknown origin) using GFP-ATF2 as substrate after 1 hr by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed