BDBM50088913 5-(4-Methoxy-phenyl)-7-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine::5-(4-methoxyphenyl)-7-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine::CHEMBL176705
SMILES COc1ccc(cc1)-c1cn(-c2ccccc2)c2ncnc(N)c12
InChI Key InChIKey=KOFGCEDKGQUYDQ-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50088913
Affinity DataIC50: 400nMAssay Description:Tested in vitro for inhibition of non-receptor tyrosine kinase v-AblMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Novartis Pharma
Curated by ChEMBL
Novartis Pharma
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Tested in vitro for inhibition of KDR-receptor tyrosine kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Tested in vitro for inhibition of EGF-receptor tyrosine kinaseMore data for this Ligand-Target Pair
Affinity DataIC50: 158nMAssay Description:Inhibition of c-Src kinase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Tested in vitro for inhibition of serine/threonine kinase Cdc2More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
Novartis Pharma
Curated by ChEMBL
Novartis Pharma
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Tested for inhibition of protein tyrosine kinase c-Src phosphorylationMore data for this Ligand-Target Pair