BDBM50089761 (R)-1-[2-(1H-Indol-3-yl)-2-oxo-acetyl]-piperidine-3-carboxylic acid benzyl-methyl-amide::CHEMBL28730

SMILES CN(Cc1ccccc1)C(=O)[C@@H]1CCCN(C1)C(=O)C(=O)c1c[nH]c2ccccc12

InChI Key InChIKey=OWTXLWRGHNAFHX-GOSISDBHSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50089761   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50089761((R)-1-[2-(1H-Indol-3-yl)-2-oxo-acetyl]-piperidine-...)
Affinity DataKi:  7.30nMAssay Description:Binding affinity evaluated by ability to displace [3H]Ro-151788 from recombinant human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2 expr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50089761((R)-1-[2-(1H-Indol-3-yl)-2-oxo-acetyl]-piperidine-...)
Affinity DataKi:  19nMAssay Description:Binding affinity evaluated by ability to displace [3H]-Ro-15-1788 from recombinant human Gamma-aminobutyric acid A receptor alpha-2-beta-3-gamma-2 ex...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50089761((R)-1-[2-(1H-Indol-3-yl)-2-oxo-acetyl]-piperidine-...)
Affinity DataKi:  50nMAssay Description:Binding affinity evaluated by ability to displace [3H]Ro-151788 from recombinant human Gamma-aminobutyric acid A receptor alpha-3-beta-3-gamma-2 expr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed