BDBM50090918 CHEMBL3581877

SMILES CN(C)CCCn1c2-c3ccccc3C(=O)c2c2ccncc2c1=O

InChI Key InChIKey=DUBDZPXTUCXYHD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50090918   

TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50090918(CHEMBL3581877)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of recombinant TPD1 (unknown origin) activity using 3'-phosphotyrosine-containing 5'-[32P]-labeled single-stranded DNA oligonucleotide by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50090918(CHEMBL3581877)
Affinity DataIC50:  6.30E+4nMAssay Description:Inhibition of recombinant TDP1 (unknown origin) using single stranded 5'-[32P]-labeled DNA containing 3'-phosphotyrosine as substrate after 15 mins b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50090918(CHEMBL3581877)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of human recombinant TDP2 using 19-mer single stranded DNA containing 5'-phosphotyrosine as substrate after 15 mins by PAGEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosyl-DNA phosphodiesterase 2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50090918(CHEMBL3581877)
Affinity DataIC50:  3.70E+4nMAssay Description:Inhibition of human recombinant TPD2 activity using 5'phosphotyrosine-containing 19-mer single-stranded oligonucleotide DNA substrate by PAGE assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed