BDBM50091331 CHEMBL3582255::US9872852, Example 122

SMILES Cc1c(COc2ccc(CNCC3CCC(=O)N3)cc2)cccc1-c1ccccc1

InChI Key InChIKey=NIVJEFTUALCIHL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091331   

TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50091331(CHEMBL3582255 | US9872852, Example 122)
Affinity DataIC50:  1.01E+3nMAssay Description:Binding affinity to His-tagged PD-L1 (unknown origin) assessed as inhibition of interaction with PD1 preincubated for 15 mins followed by PD1 additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50091331(CHEMBL3582255 | US9872852, Example 122)
Affinity DataIC50:  555nMAssay Description:All binding studies were performed in an HTRF assay buffer consisting of dPBS supplemented with 0.1% (withv) bovine serum albumin and 0.05% (v/v) Twe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50091331(CHEMBL3582255 | US9872852, Example 122)
Affinity DataIC50:  5.51E+3nMAssay Description:All binding studies were performed in an HTRF assay buffer consisting of dPBS supplemented with 0.1% (withv) bovine serum albumin and 0.05% (v/v) Twe...More data for this Ligand-Target Pair
In DepthDetails US Patent