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BDBM50091515 Aminoalkyl adenylate and aminoacyl sulfamate analogue

SMILES: N[C@@H](CCCNC(N)=[NH2+])C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

InChI Key: InChIKey=BPKLMCNLHSJSEL-JVEUSOJLSA-O

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50091515   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arginyl-tRNA synthetase


(Homo sapiens (Human))
BDBM50091515
PNG
(Aminoalkyl adenylate and aminoacyl sulfamate analo...)
Show SMILES N[C@@H](CCCNC(N)=[NH2+])C(=O)NS(=O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
Show InChI InChI=1S/C16H26N10O7S/c17-7(2-1-3-21-16(19)20)14(29)25-34(30,31)32-4-8-10(27)11(28)15(33-8)26-6-24-9-12(18)22-5-23-13(9)26/h5-8,10-11,15,27-28H,1-4,17H2,(H,25,29)(H2,18,22,23)(H4,19,20,21)/p+1/t7-,8+,10+,11+,15+/m0/s1
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PC cid
PC sid
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Similars

Article
PubMed
n/an/a 4.5n/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals Ltd

Curated by ChEMBL


Assay Description
Inhibitory activity against cognate Staphylococcus aureus Arginyl-tRNA synthetase


Bioorg Med Chem Lett 10: 1871-4 (2000)


Article DOI: 10.1016/s0960-894x(00)00360-7
BindingDB Entry DOI: 10.7270/Q2TX3FWJ
More data for this
Ligand-Target Pair