BDBM50091620 1-[2-Hydroxy-4-(2-hydroxy-indan-1-ylcarbamoyl)-5-phenyl-pentyl]-4-(2-methylsulfanyl-pyridin-3-ylmethyl)-piperazine-2-carboxylic acid tert-butylamide::CHEMBL112257

SMILES CSc1ncccc1CN1CCN(C[C@@H](O)C[C@@H](Cc2ccccc2)C(=O)NC2[C@H](O)Cc3ccccc23)[C@@H](C1)C(=O)NC(C)(C)C

InChI Key InChIKey=SUVMGYUHKSTITP-CAXFYQCDSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50091620   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091620(1-[2-Hydroxy-4-(2-hydroxy-indan-1-ylcarbamoyl)-5-p...)
Affinity DataIC50:  0.260nMAssay Description:Inhibition of HIV-1 protease in vitro.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed