BDBM50091628 5-{3-[4-(4-Methoxy-benzyl)-piperidin-1-yl]-prop-1-ynyl}-1,3-dihydro-benzoimidazol-2-one::CHEMBL326568

SMILES COc1ccc(CC2CCN(CC#Cc3ccc4[nH]c(=O)[nH]c4c3)CC2)cc1

InChI Key InChIKey=DHGIUNURIAYCCZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50091628   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50091628(5-{3-[4-(4-Methoxy-benzyl)-piperidin-1-yl]-prop-1-...)
Affinity DataIC50:  9.90E+3nMAssay Description:Displacement of [3H]-raclopride at Dopamine receptor D2 in brain striata (n=1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50091628(5-{3-[4-(4-Methoxy-benzyl)-piperidin-1-yl]-prop-1-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2C NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50091628(5-{3-[4-(4-Methoxy-benzyl)-piperidin-1-yl]-prop-1-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2A NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50091628(5-{3-[4-(4-Methoxy-benzyl)-piperidin-1-yl]-prop-1-...)
Affinity DataIC50:  26nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed