BDBM50091637 5-(3-(4-benzylpiperidin-1-yl)prop-1-ynyl)-1H-benzo[d]imidazol-2(3H)-one::5-[3-(4-Benzyl-piperidin-1-yl)-prop-1-ynyl]-1,3-dihydro-benzoimidazol-2-one::CHEMBL117260

SMILES O=c1[nH]c2ccc(cc2[nH]1)C#CCN1CCC(Cc2ccccc2)CC1

InChI Key InChIKey=JJEXWPHPFZLTCU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50091637   

TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50091637(5-(3-(4-benzylpiperidin-1-yl)prop-1-ynyl)-1H-benzo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2C NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50091637(5-(3-(4-benzylpiperidin-1-yl)prop-1-ynyl)-1H-benzo...)
Affinity DataIC50:  5.30nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50091637(5-(3-(4-benzylpiperidin-1-yl)prop-1-ynyl)-1H-benzo...)
Affinity DataIC50:  2.60E+3nMAssay Description:Displacement of [3H]-raclopride at Dopamine receptor D2 in brain striata (n=1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50091637(5-(3-(4-benzylpiperidin-1-yl)prop-1-ynyl)-1H-benzo...)
Affinity DataIC50:  3.50E+4nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2A NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed