BDBM50091643 5-{3-[4-(4-Chloro-benzyl)-piperidin-1-yl]-prop-1-ynyl}-1,3-dihydro-benzoimidazol-2-one::CHEMBL325825

SMILES Clc1ccc(CC2CCN(CC#Cc3ccc4[nH]c(=O)[nH]c4c3)CC2)cc1

InChI Key InChIKey=QAHMMZQSMDIJJU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50091643   

TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50091643(5-{3-[4-(4-Chloro-benzyl)-piperidin-1-yl]-prop-1-y...)
Affinity DataIC50:  3.70E+3nMAssay Description:Displacement of [3H]-raclopride at Dopamine receptor D2 in brain striata (n=1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1(Homo sapiens (Human))
Cocensys

Curated by ChEMBL
LigandPNGBDBM50091643(5-{3-[4-(4-Chloro-benzyl)-piperidin-1-yl]-prop-1-y...)
Affinity DataIC50:  19nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed