BDBM50091739 (S)-3-{2-[(R)-2-Oxo-1-(2-piperidin-4-yl-ethyl)-piperidin-3-yl]-acetylamino}-pent-4-ynoic acid::CHEMBL58713

SMILES OC(=O)C[C@H](NC(=O)C[C@H]1CCCN(CCC2CCNCC2)C1=O)C#C

InChI Key InChIKey=PQBZVJZWTNXWCX-HZPDHXFCSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50091739   

TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091739((S)-3-{2-[(R)-2-Oxo-1-(2-piperidin-4-yl-ethyl)-pip...)
Affinity DataKd:  6.10nMAssay Description:Binding affinity to resting form of alpha IIb/beta3 integrin by flow cytometry using fluorescein ligand L-726,745 displacement from human platelets.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091739((S)-3-{2-[(R)-2-Oxo-1-(2-piperidin-4-yl-ethyl)-pip...)
Affinity DataKd:  0.340nMAssay Description:Inhibition of aggregation of human gel-filtered platelets measured by light transmittance method at 37 degrees C.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091739((S)-3-{2-[(R)-2-Oxo-1-(2-piperidin-4-yl-ethyl)-pip...)
Affinity DataIC50:  15nMAssay Description:Inhibition of aggregation of human gel-filtered platelets measured by light transmittance method at 37 degrees C.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed