BDBM50092250 CHEMBL302279::[4-Amino-7-cyclopentyl-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-methanol

SMILES Nc1ncnc2n(C3CCCC3)c(CO)c(-c3ccc(Oc4ccccc4)cc3)c12

InChI Key InChIKey=URRPZVFWMHHCKB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50092250   

TargetVascular endothelial growth factor receptor 2(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092250(CHEMBL302279 | [4-Amino-7-cyclopentyl-5-(4-phenoxy...)
Affinity DataIC50:  1.08E+3nMAssay Description:Inhibitory activity against vascular endothelial growth factor receptor 2 (VEGFR2) at a concentration of 5 microM ATP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTyrosine-protein kinase Lck(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092250(CHEMBL302279 | [4-Amino-7-cyclopentyl-5-(4-phenoxy...)
Affinity DataIC50:  17nMAssay Description:Inhibitory activity against p56 Lck tyrosine kinase at a concentration of 5 microM ATP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAngiopoietin-1 receptor(Human)
Basf Bioresearch

Curated by ChEMBL
LigandPNGBDBM50092250(CHEMBL302279 | [4-Amino-7-cyclopentyl-5-(4-phenoxy...)
Affinity DataIC50:  360nMAssay Description:Inhibitory activity against tie-2 at a concentration of 5 microM ATP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed