BDBM50092254 7-Isopropyl-5-[4-(2-nitro-phenoxy)-phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine::CHEMBL304113
SMILES CC(C)n1cc(-c2ccc(Oc3ccccc3[N+]([O-])=O)cc2)c2c(N)ncnc12
InChI Key InChIKey=PWEMILVNKQAISL-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50092254
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Basf Bioresearch
Curated by ChEMBL
Basf Bioresearch
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibitory activity against vascular endothelial growth factor receptor 2 (VEGFR2) at a concentration of 5 microM ATP.More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of p56 Lck tyrosine kinase (catalytic domain)More data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory activity against tie-2 at a concentration of 5 microM ATP.More data for this Ligand-Target Pair
Affinity DataIC50: <3nMAssay Description:Inhibition of p56 Lck tyrosine kinase (catalytic domain)More data for this Ligand-Target Pair