BDBM50092779 CHEMBL3586391
SMILES COCCN1C(=O)CNc2ncc(nc12)-c1ccc(nc1)C(C)(C)O
InChI Key InChIKey=XSQAJVDTZWOBMX-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50092779
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Celgene
Curated by ChEMBL
Celgene
Curated by ChEMBL
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of PI3K-alpha (unknown origin) by mobility shift assayMore data for this Ligand-Target Pair
Affinity DataIC50: 175nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 650nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation after 1 hrMore data for this Ligand-Target Pair