BDBM50093068 CHEMBL3586559

SMILES Cc1nc(ccc1-c1cnc2NCC(=O)N(CCN3CCOCC3)c2n1)-c1nc[nH]n1

InChI Key InChIKey=SXJWIRIRCLXOIF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50093068   

TargetFKBP12A/mTOR(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50093068(CHEMBL3586559)
Affinity DataIC50:  54nMAssay Description:Inhibition of mTORC1 in human PC3 cells assessed as inhibition of p70S6K phosphorylation after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM50093068(CHEMBL3586559)
Affinity DataIC50:  37nMAssay Description:Inhibition of mTOR (unknown origin) by HTR-FRET substrate phosphorylation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed