BDBM50094510 CHEMBL3589019

SMILES Nc1nonc1NC(=O)Cn1c2ccccc2c2nc3nonc3nc12

InChI Key InChIKey=GDVHPNKSEYEMPJ-UHFFFAOYSA-N

Data  4 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50094510   

TargetCatenin beta-1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50094510(CHEMBL3589019)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of N-terminally His6-tagged human beta-catenin (residues 138-686)/C-terminally biotinylated human Tcf4 (residues 7-51) interaction after 4...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50094510(CHEMBL3589019)
Affinity DataKi:  7.20E+3nMAssay Description:Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein labeled human wild-type Tcf4 (residues 7-51) interaction after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50094510(CHEMBL3589019)
Affinity DataKi:  3.10E+4nMAssay Description:Inhibition of human beta-catenin V511S mutant/human wild-type Tcf4 interaction after 1.5 hrs by FP competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50094510(CHEMBL3589019)
Affinity DataKi:  8.80E+4nMAssay Description:Inhibition of human beta-catenin R469A mutant/human wild-type Tcf4 interaction after 1.5 hrs by FP competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50094510(CHEMBL3589019)
Affinity DataIC50:  5.50E+5nMAssay Description:Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein-labeled human E-cadherin (residues 819-873) interaction by FP ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50094510(CHEMBL3589019)
Affinity DataIC50:  6.30E+5nMAssay Description:Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein-labeled human APC-R3 (residues 1477-1519) interaction by FP co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatenin beta-1(Homo sapiens (Human))
University Of Utah

Curated by ChEMBL
LigandPNGBDBM50094510(CHEMBL3589019)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein labeled human wild-type Tcf4 (residues 7-51) interaction after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed