BDBM50094514 1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-trifluoromethoxy-benzyl)-amino]-propan-2-ol::1,1,1-trifluoro-3-((3-phenoxyphenyl)(3-(trifluoromethoxy)benzyl)amino)propan-2-ol::3-((3-(trifluoromethoxy)benzyl)(3-phenoxyphenyl)amino)-1,1,1-trifluoropropan-2-ol::CHEMBL127895

SMILES OC(CN(Cc1cccc(OC(F)(F)F)c1)c1cccc(Oc2ccccc2)c1)C(F)(F)F

InChI Key InChIKey=STUPFEVEXRNAEM-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50094514   

TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50094514(1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-trifluoro...)
Affinity DataIC50:  4.00E+4nMAssay Description:Tested for inhibiting CETP-mediated transfer of [3H]-CE from HDL to LDL in vitro under buffered assay conditions in human serum.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50094514(1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-trifluoro...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of recombinant human CETP-mediated transfer of [3H]-CE from HDL to LDLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Oryctolagus cuniculus)
Al-Zaytoonah Private University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50094514(1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-trifluoro...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of CETP in rabbit serum after 1 hr by fluorescent cholesteryl esters transfer assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50094514(1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-trifluoro...)
Affinity DataIC50:  1.00E+3nMAssay Description:Concentration required for 50% inhibition of cholesteryl ester transfer protein in presence of buffer.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50094514(1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-trifluoro...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of CETPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholesteryl ester transfer protein(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50094514(1,1,1-Trifluoro-3-[(3-phenoxy-phenyl)-(3-trifluoro...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of cholesteryl ester transfer protein in presence of human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed