BDBM50095227 (6,7-Dimethoxy-quinazolin-4-yl)-(4-phenoxy-phenyl)-amine::6,7-dimethoxy-N-(4-phenoxyphenyl)quinazolin-4-amine::CHEMBL97771::US10548897, Compound 2
SMILES COc1cc2ncnc(Nc3ccc(Oc4ccccc4)cc3)c2cc1OC
InChI Key InChIKey=DMWVGXGXHPOEPT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50095227
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of EPH receptor B2 using ELISAMore data for this Ligand-Target Pair
Affinity DataKd: 5.84E+4nMAssay Description:Equilibrium binding constant for EPH receptor B2More data for this Ligand-Target Pair
Affinity DataIC50: 602nMAssay Description:The ATP-biotin assay was performed in buffer containing 25 mM Tris pH 7.5, 150 mM NaCl, 10 mM MgCl2, and 2% DMSO. Purified hKSR2-rMEK1 was assayed at...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Gallus gallus (Chicken))
University Of Dundee
Curated by ChEMBL
University Of Dundee
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of Src in the presence of 50uM ATPMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1/RAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Wyeth-Ayerst Research
Curated by ChEMBL
Wyeth-Ayerst Research
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ERK phosphorylation in coupled Raf-MEK-ERK ELISA (Weakly active)More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
University Of Dundee
Curated by ChEMBL
University Of Dundee
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of RIP2 in the presence of 100uM ATPMore data for this Ligand-Target Pair