BDBM50095317 2-Methoxy-5-(3,4,5-trimethoxy-phenoxymethyl)-phenol::CHEMBL345556

SMILES COc1ccc(COc2cc(OC)c(OC)c(OC)c2)cc1O

InChI Key InChIKey=JXIPAFNBJWGSFY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50095317   

TargetTubulin beta-1 chain(Homo sapiens (Human))
University Of Salford

Curated by ChEMBL
LigandPNGBDBM50095317(2-Methoxy-5-(3,4,5-trimethoxy-phenoxymethyl)-pheno...)
Affinity DataIC50:  7.20E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A/beta chain(Sus scrofa (Pig))
The University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50095317(2-Methoxy-5-(3,4,5-trimethoxy-phenoxymethyl)-pheno...)
Affinity DataIC50:  6.60E+3nMAssay Description:Effect on tubulin binding and the concentration required to cause 50% decrease in tubulin assembly at 350 nm.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A/beta chain(Sus scrofa (Pig))
The University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50095317(2-Methoxy-5-(3,4,5-trimethoxy-phenoxymethyl)-pheno...)
Affinity DataIC50:  3.60E+4nMAssay Description:Concentration required to cause 50% decrease in the binding of [3H]colchicine from purified porcine tubulin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed