BDBM50095450 2-[6-Amino-1-(2-amino-ethyl)-hexylsulfanylmethyl]-5-(6-amino-purin-9-yl)-tetrahydro-furan-3,4-diol::CHEMBL330673

SMILES NCCCCCC(CCN)SC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

InChI Key InChIKey=YETXSQDQSWLLJR-JJPFLPBXSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50095450   

TargetSpermidine synthase(Rattus norvegicus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50095450(2-[6-Amino-1-(2-amino-ethyl)-hexylsulfanylmethyl]-...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of Spermidine aminopropyltransferase (SAPT) in rat liver.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSpermidine synthase(Rattus norvegicus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50095450(2-[6-Amino-1-(2-amino-ethyl)-hexylsulfanylmethyl]-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Putrescine aminopropyl transferase (PAPT) in rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSpermidine synthase(Rattus norvegicus)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50095450(2-[6-Amino-1-(2-amino-ethyl)-hexylsulfanylmethyl]-...)
Affinity DataIC50:  400nMAssay Description:Inhibitory activity against spermidine synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSpermine synthase(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50095450(2-[6-Amino-1-(2-amino-ethyl)-hexylsulfanylmethyl]-...)
Affinity DataIC50:  50nMAssay Description:Inhibitory activity against spermine synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSpermidine synthase(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50095450(2-[6-Amino-1-(2-amino-ethyl)-hexylsulfanylmethyl]-...)
Affinity DataIC50:  250nMAssay Description:Inhibition of prokaryotic Escherichia coli Putrescine aminopropyltransferase was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed