BDBM50095631 CHEMBL146332::[3-(3,4-Dichloro-phenyl)-indan-1-yl]-dimethyl-amine;chloride

SMILES CN[C@H]1C[C@H](c2ccccc12)c1ccc(Cl)c(Cl)c1

InChI Key InChIKey=SVFXPTLYMIXFRX-BBRMVZONSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50095631   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pharm-Eco Laboratories

Curated by ChEMBL
LigandPNGBDBM50095631(CHEMBL146332 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...)
Affinity DataKi:  4nMAssay Description:Inhibition of reuptake of [3H]5-HT (20 nM) by serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pharm-Eco Laboratories

Curated by ChEMBL
LigandPNGBDBM50095631(CHEMBL146332 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...)
Affinity DataKi:  38nMAssay Description:Binding affinity against cloned serotonin human transporter using 40-80 PM [125I]RTIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pharm-Eco Laboratories

Curated by ChEMBL
LigandPNGBDBM50095631(CHEMBL146332 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...)
Affinity DataKi:  130nMAssay Description:Inhibition of reuptake of [3H]-NE (20 nM) by norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pharm-Eco Laboratories

Curated by ChEMBL
LigandPNGBDBM50095631(CHEMBL146332 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...)
Affinity DataKi:  290nMAssay Description:Binding affinity against cloned human dopamine transporter using 40-80 pM [125I]RTI.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pharm-Eco Laboratories

Curated by ChEMBL
LigandPNGBDBM50095631(CHEMBL146332 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...)
Affinity DataKi:  500nMAssay Description:Inhibition of reuptake of [3H]DA (20 nM) by dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pharm-Eco Laboratories

Curated by ChEMBL
LigandPNGBDBM50095631(CHEMBL146332 | [3-(3,4-Dichloro-phenyl)-indan-1-yl...)
Affinity DataKi:  600nMAssay Description:Binding affinity against norepinephrine cloned human transporter using 40-80 pM [125I]RTIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed