BDBM50095994 3-Cyano-7-hydroxycoumarin (2)::7-Hydroxy-2-oxo-2H-chromene-3-carbonitrile::CHEMBL150302
SMILES Oc1ccc2cc(C#N)c(=O)oc2c1
InChI Key InChIKey=IJQYTHQDUDCJEQ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 50095994
Affinity DataKi: 240nM ΔG°: -8.39kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Affinity DataKi: 370nM ΔG°: -8.15kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 5B, mitochondrial(Homo sapiens (Human))
Ecole Nationale Superieure De Chimie De Montpellier
Ecole Nationale Superieure De Chimie De Montpellier
Affinity DataKi: 1.87E+3nM ΔG°: -7.26kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 5A, mitochondrial(Homo sapiens (Human))
Ecole Nationale Superieure De Chimie De Montpellier
Ecole Nationale Superieure De Chimie De Montpellier
Affinity DataKi: 2.27E+3nM ΔG°: -7.15kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
TargetMacrophage migration inhibitory factor(Homo sapiens (Human))
Yamanouchi Pharmaceutical
Curated by ChEMBL
Yamanouchi Pharmaceutical
Curated by ChEMBL
Affinity DataKi: 2.90E+3nMAssay Description:Inhibitory activity against tautomerase macrophage migration inhibitory factor (MIF)More data for this Ligand-Target Pair
Affinity DataKi: 2.98E+3nM ΔG°: -7.00kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 13(Homo sapiens (Human))
Ecole Nationale Superieure De Chimie De Montpellier
Ecole Nationale Superieure De Chimie De Montpellier
Affinity DataKi: 5.34E+3nM ΔG°: -6.68kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 14(Homo sapiens (Human))
Ecole Nationale Superieure De Chimie De Montpellier
Ecole Nationale Superieure De Chimie De Montpellier
Affinity DataKi: 6.25E+3nM ΔG°: -6.59kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Ecole Nationale Superieure De Chimie De Montpellier
Ecole Nationale Superieure De Chimie De Montpellier
Affinity DataKi: 7.11E+3nM ΔG°: -6.52kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Affinity DataKi: 1.04E+5nM ΔG°: -5.05kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Affinity DataKi: >2.00E+5nM ΔG°: >-4.69kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
Affinity DataKi: >2.00E+5nM ΔG°: >-4.69kcal/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair