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BDBM50096632 CHEMBL3577274

SMILES: NC(=O)Cn1c2C[C@@H](CCc2c2cc(Cl)ccc12)C(O)=O

InChI Key: InChIKey=WEITVQPGVPEPAZ-MRVPVSSYSA-N

Data: 1 KI  1 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50096632   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA polymerase III subunit beta


(Escherichia coli (strain K12))
BDBM50096632
PNG
(CHEMBL3577274)
Show SMILES NC(=O)Cn1c2C[C@@H](CCc2c2cc(Cl)ccc12)C(O)=O
Show InChI InChI=1S/C15H15ClN2O3/c16-9-2-4-12-11(6-9)10-3-1-8(15(20)21)5-13(10)18(12)7-14(17)19/h2,4,6,8H,1,3,5,7H2,(H2,17,19)(H,20,21)/t8-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem

Patents


Similars

PDB
Article
PubMed
2.04E+5n/an/an/an/an/an/an/an/a



The University of Wollongong and The Illawarra Health and Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DNA sliding clamp protein using N-fluorescein (FAM)-QLDLF-OH tracer by fluorescence polarization assay


J Med Chem 58: 4693-702 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00232
BindingDB Entry DOI: 10.7270/Q2KK9DJ9
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
DNA polymerase III subunit beta


(Escherichia coli (strain K12))
BDBM50096632
PNG
(CHEMBL3577274)
Show SMILES NC(=O)Cn1c2C[C@@H](CCc2c2cc(Cl)ccc12)C(O)=O
Show InChI InChI=1S/C15H15ClN2O3/c16-9-2-4-12-11(6-9)10-3-1-8(15(20)21)5-13(10)18(12)7-14(17)19/h2,4,6,8H,1,3,5,7H2,(H2,17,19)(H,20,21)/t8-/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem

Patents


Similars

PDB
Article
PubMed
n/an/a 3.68E+5n/an/an/an/an/an/a



The University of Wollongong and The Illawarra Health and Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Escherichia coli DNA sliding clamp protein using N-fluorescein (FAM)-QLDLF-OH tracer by fluorescence polarization assay


J Med Chem 58: 4693-702 (2015)


Article DOI: 10.1021/acs.jmedchem.5b00232
BindingDB Entry DOI: 10.7270/Q2KK9DJ9
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)