BDBM50097096 2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline-4-carboxylic acid::CHEMBL357355

SMILES Cc1cc(Cl)cc2c(cc(nc12)-c1ccc(Br)cc1)C(O)=O

InChI Key InChIKey=TZOKMWXGAXPQIM-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50097096   

TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097096(2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline-4-c...)
Affinity DataKi:  5.10nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097096(2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline-4-c...)
Affinity DataKi:  15nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional glutamate/proline--tRNA ligase(Human)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097096(2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline-4-c...)
Affinity DataIC50: >2.00E+4nMAssay Description:Aminoacylation activity against human prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProline--tRNA ligase, cytoplasmic(Yeast)
Cubist Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50097096(2-(4-Bromo-phenyl)-6-chloro-8-methyl-quinoline-4-c...)
Affinity DataIC50:  5nMAssay Description:Aminoacylation activity against Candida albicans prolyl-tRNA synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed