BDBM50097127 CHEMBL3580949

SMILES NC1CCN(CC1)c1nc(Nc2cc([nH]n2)C2CC2)c2sccc2n1

InChI Key InChIKey=DNTNKJATBLJMII-UHFFFAOYSA-N

Data  2 KI

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50097127   

TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Shanghai Chempartner

Curated by ChEMBL

LigandBDBM50097127(CHEMBL3580949)Copy SMILESCopy InChI

Affinity DataKi:  12nMAssay Description:Inhibition of human recombinant PAK4 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate assessed as substrate phosphorylation...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetSerine/threonine-protein kinase PAK 1(Homo sapiens (Human))
Shanghai Chempartner

Curated by ChEMBL

LigandBDBM50097127(CHEMBL3580949)Copy SMILESCopy InChI

Affinity DataKi:  22nMAssay Description:Inhibition of human recombinant PAK1 kinase domain using coumarin/fluorescein-labeled FRET peptide as substrate assessed as substrate phosphorylation...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
Copy BDB DOI