BDBM50097884 (1-hydroxy-1-phosphono-butyl)-phosphonic acid::1-hydroxybutane-1,1-diyldiphosphonic acid::CHEMBL52761

SMILES CCCC(O)(P(O)(O)=O)P(O)(O)=O

InChI Key InChIKey=RUPZRJCPTQGQRU-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50097884   

TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50097884((1-hydroxy-1-phosphono-butyl)-phosphonic acid | 1-...)
Affinity DataKi:  5.04E+3nMAssay Description:Binding affinity of the compound towards T. cruzi farnesyl pyrophosphate synthase (TcFPPS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl pyrophosphate synthase(Homo sapiens (Human))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50097884((1-hydroxy-1-phosphono-butyl)-phosphonic acid | 1-...)
Affinity DataIC50:  6.20E+5nMAssay Description:Inhibitory activity against the human recombinant geranylgeranyl diphosphate synthase (GGPPSase).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetH(+)-exporting diphosphatase(Trypanosoma brucei)
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50097884((1-hydroxy-1-phosphono-butyl)-phosphonic acid | 1-...)
Affinity DataIC50:  2.15E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei soluble vacuolar pyrophosphatase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50097884((1-hydroxy-1-phosphono-butyl)-phosphonic acid | 1-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl pyrophosphate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFarnesyl pyrophosphate synthase(Homo sapiens (Human))
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50097884((1-hydroxy-1-phosphono-butyl)-phosphonic acid | 1-...)
Affinity DataIC50:  4.28E+4nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl pyrophosphate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyprenyl synthetase family protein(Plasmodium falciparum (isolate 3D7))
University Of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50097884((1-hydroxy-1-phosphono-butyl)-phosphonic acid | 1-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory activity against Leishmania major Farnesyl diphosphate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed