BDBM50098519 (6-Ethyl-thieno[2,3-d]pyrimidin-4-yl)-(5-methyl-[1,3,4]thiadiazol-2-yl)-amine::CHEMBL269495

SMILES CCc1cc2c(Nc3nnc(C)s3)ncnc2s1

InChI Key InChIKey=BDGZXAUQGBHBST-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50098519   

TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098519((6-Ethyl-thieno[2,3-d]pyrimidin-4-yl)-(5-methyl-[1...)
Affinity DataIC50:  4.20E+4nMAssay Description:In vitro potency against TNF alpha induced expression of Selectin E on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098519((6-Ethyl-thieno[2,3-d]pyrimidin-4-yl)-(5-methyl-[1...)
Affinity DataIC50:  9.20E+4nMAssay Description:In vitro potency against TNF alpha induced expresion of intercellular adhesion molecule-1 on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098519((6-Ethyl-thieno[2,3-d]pyrimidin-4-yl)-(5-methyl-[1...)
Affinity DataIC50:  1.90E+4nMAssay Description:In vitro potency against TNF alpha induced expresion of VCAM-1 on human vascular endothelial cells using CAM ELISA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed