BDBM50098752 1-(4-Acetyl-piperazin-1-yl)-3-{3-chloro-4-[1-(2-methoxy-ethyl)-1H-indol-5-ylsulfanyl]-phenyl}-propenone::CHEMBL418006

SMILES COCCn1ccc2cc(Sc3ccc(\C=C\C(=O)N4CCN(CC4)C(C)=O)cc3Cl)ccc12

InChI Key InChIKey=XWTGFUGJJCIZRY-XBXARRHUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098752   

TargetIntegrin alpha-L/beta-2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50098752(1-(4-Acetyl-piperazin-1-yl)-3-{3-chloro-4-[1-(2-me...)
Affinity DataIC50:  60nMAssay Description:Inhibition of JY-8 cell adhesion via leukocyte function associated antigen 1 (LFA-1) to ICAM-1, range (30-60)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed