BDBM50098840 2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-1-yl]-N-(1-benzyl-2-oxo-2-thiazol-2-yl-ethyl)-acetamide::CHEMBL284665

SMILES Nc1cnc(-c2ccc(F)cc2)n(CC(=O)NC(Cc2ccccc2)C(=O)c2nccs2)c1=O

InChI Key InChIKey=ISCYRTVYNLJNLW-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50098840   

TargetChymotrypsinogen A(Bos taurus (bovine))
Welfide

Curated by ChEMBL
LigandPNGBDBM50098840(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibitory activity against alpha chymotrypsin from bovine pancreas.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Welfide

Curated by ChEMBL
LigandPNGBDBM50098840(2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-...)
Affinity DataKi:  3.85E+3nMAssay Description:Inhibitory activity evaluated against chymase from human heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed