BDBM50098918 (R)-1-Benzyl-3-(4-methoxy-benzenesulfonyl)-6-oxo-hexahydro-pyrimidine-4-carboxylic acid hydroxyamide::1-BENZYL-3-(4-METHOXY-BENZENESULFONYL)-6-OXO-HEXAHYDRO-PYRIMIDINE-4-CARBOXYLIC ACID HYDROXYAMIDE::CHEMBL7390

SMILES COc1ccc(cc1)S(=O)(=O)N1CN(Cc2ccccc2)C(=O)C[C@@H]1C(=O)NO

InChI Key InChIKey=SUSMVCKSLVPRCL-QGZVFWFLSA-N

Data  8 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50098918   

TargetInterstitial collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098918((R)-1-Benzyl-3-(4-methoxy-benzenesulfonyl)-6-oxo-h...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098918((R)-1-Benzyl-3-(4-methoxy-benzenesulfonyl)-6-oxo-h...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098918((R)-1-Benzyl-3-(4-methoxy-benzenesulfonyl)-6-oxo-h...)
Affinity DataIC50:  3.10nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50098918((R)-1-Benzyl-3-(4-methoxy-benzenesulfonyl)-6-oxo-h...)
Affinity DataIC50:  1nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pomona College

Curated by ChEMBL
LigandPNGBDBM50098918((R)-1-Benzyl-3-(4-methoxy-benzenesulfonyl)-6-oxo-h...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human Matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098918((R)-1-Benzyl-3-(4-methoxy-benzenesulfonyl)-6-oxo-h...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of Matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Rattus norvegicus)
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098918((R)-1-Benzyl-3-(4-methoxy-benzenesulfonyl)-6-oxo-h...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Procter And Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098918((R)-1-Benzyl-3-(4-methoxy-benzenesulfonyl)-6-oxo-h...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed