BDBM50099127 5-Methyl-5-phenyl-pyrimidine-2,4,6-trione::CHEMBL329617

SMILES CC1(C(=O)NC(=O)NC1=O)c1ccccc1

InChI Key InChIKey=LSAOZCAKUIANSQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50099127   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099127(5-Methyl-5-phenyl-pyrimidine-2,4,6-trione | CHEMBL...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of Gelatinase B, matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099127(5-Methyl-5-phenyl-pyrimidine-2,4,6-trione | CHEMBL...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of Gelatinase A, matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099127(5-Methyl-5-phenyl-pyrimidine-2,4,6-trione | CHEMBL...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50099127(5-Methyl-5-phenyl-pyrimidine-2,4,6-trione | CHEMBL...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of matrilysin, Matrix metalloproteinase-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed