BDBM50100086 CHEMBL33977::[2,6-Dimethyl-4-(3-methyl-4-oxo-3,4-dihydro-phthalazin-1-yl)-phenoxy]-acetic acid methyl ester

SMILES COC(=O)COc1c(C)cc(cc1C)-c1nn(C)c(=O)c2ccccc12

InChI Key InChIKey=FDJBYAHLPYLRKD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50100086   

TargetNeutrophil collagenase(Homo sapiens (Human))
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100086(CHEMBL33977 | [2,6-Dimethyl-4-(3-methyl-4-oxo-3,4-...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100086(CHEMBL33977 | [2,6-Dimethyl-4-(3-methyl-4-oxo-3,4-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100086(CHEMBL33977 | [2,6-Dimethyl-4-(3-methyl-4-oxo-3,4-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100086(CHEMBL33977 | [2,6-Dimethyl-4-(3-methyl-4-oxo-3,4-...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100086(CHEMBL33977 | [2,6-Dimethyl-4-(3-methyl-4-oxo-3,4-...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed