BDBM50100283 2-(3-Ethynyl-phenoxy)-4-imidazol-1-ylmethyl-benzonitrile::CHEMBL22080
SMILES C#Cc1cccc(Oc2cc(Cn3ccnc3)ccc2C#N)c1
InChI Key InChIKey=IBIUCSOTYPMCEO-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50100283
TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 27nMAssay Description:Inhibition of rate of incorporation of [3H]-FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of rate of incorporation of [3H]-GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-tran...More data for this Ligand-Target Pair