BDBM50100519 CHEMBL3327067::US10377744, Compound No. 2391
SMILES CC[C@H](C)C(=O)N1CCC(CC1)NC(=O)Nc1ccc(cc1)C(F)(F)F
InChI Key InChIKey=GYIFHGGYNPKLFC-LBPRGKRZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50100519
Affinity DataKi: 0.220nMAssay Description:FRET assays to determine Ki for the compounds of Table I were carried out as described previously (Lee et al. Analytical Biochemistry 434 (2013) 259-...More data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase by FRET-based ACPU displacement assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Inhibition of recombinant human sEH expressed in baculovirus expression system assessed as reduction in ACPU binding incubated for 1 hr by FRET displ...More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
The Regents Of The University Of California
US Patent
The Regents Of The University Of California
US Patent
Affinity DataIC50: 17.8nMAssay Description:Trans-diphenylpropene oxide is used in a radiometric competitive assay.More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
The Regents Of The University Of California
US Patent
The Regents Of The University Of California
US Patent
Affinity DataIC50: 4nMAssay Description:fluoresence competitive assay.More data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Rattus norvegicus)
University Of California Davis
Curated by ChEMBL
University Of California Davis
Curated by ChEMBL
Affinity DataIC50: <1.30nMAssay Description:Inhibition of rat soluble epoxide hydrolase using [3H]-t-DPPO as a substrate by radiometric assayMore data for this Ligand-Target Pair