BDBM50101651 5-Isobutyryl-4-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethylamino}-2-methyl-6-phenyl-2H-pyridazin-3-one::CHEMBL80730

SMILES COc1ccccc1N1CCN(CCNc2c(C(=O)C(C)C)c(nn(C)c2=O)-c2ccccc2)CC1

InChI Key InChIKey=KSGSACNIXHZDNP-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50101651   

TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Istituto Chimico Farmaceutico E Tossicologico

Curated by ChEMBL
LigandPNGBDBM50101651(5-Isobutyryl-4-{2-[4-(2-methoxy-phenyl)-piperazin-...)
Affinity DataKi:  0.180nMAssay Description:Binding affinity towards human cloned alpha1A-adrenoceptor using [3H]-prazosin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1D adrenergic receptor(Homo sapiens (Human))
Istituto Chimico Farmaceutico E Tossicologico

Curated by ChEMBL
LigandPNGBDBM50101651(5-Isobutyryl-4-{2-[4-(2-methoxy-phenyl)-piperazin-...)
Affinity DataKi:  0.430nMAssay Description:Binding affinity towards human cloned alpha1d-adrenoceptor using [3H]-prazosin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Istituto Chimico Farmaceutico E Tossicologico

Curated by ChEMBL
LigandPNGBDBM50101651(5-Isobutyryl-4-{2-[4-(2-methoxy-phenyl)-piperazin-...)
Affinity DataKi:  0.640nMAssay Description:Binding affinity towards human cloned alpha1B-adrenoceptor using [3H]-prazosin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Istituto Chimico Farmaceutico E Tossicologico

Curated by ChEMBL
LigandPNGBDBM50101651(5-Isobutyryl-4-{2-[4-(2-methoxy-phenyl)-piperazin-...)
Affinity DataKi:  10.2nMAssay Description:Binding affinity towards human cloned 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed