BDBM50101884 2-(2-Hydroxy-5-methyl-phenyl)-1H-indole-5-carboxamidine::CHEMBL54311

SMILES Cc1ccc(O)c(c1)-c1cc2cc(ccc2[nH]1)C(N)=N

InChI Key InChIKey=ZEJKPIWHZAIROY-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50101884   

TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101884(2-(2-Hydroxy-5-methyl-phenyl)-1H-indole-5-carboxam...)
Affinity DataKi:  4.30E+3nMAssay Description:Inhibitory activity against Coagulation factor X in human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101884(2-(2-Hydroxy-5-methyl-phenyl)-1H-indole-5-carboxam...)
Affinity DataKi:  8.20E+3nMAssay Description:Inhibitory activity against trypsin in human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101884(2-(2-Hydroxy-5-methyl-phenyl)-1H-indole-5-carboxam...)
Affinity DataKi:  1.24E+4nMAssay Description:Inhibitory activity against urokinase-type plasminogen activator (microPa) in human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101884(2-(2-Hydroxy-5-methyl-phenyl)-1H-indole-5-carboxam...)
Affinity DataKi:  2.10E+4nMAssay Description:Inhibitory activity against plasmin in human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50101884(2-(2-Hydroxy-5-methyl-phenyl)-1H-indole-5-carboxam...)
Affinity DataKi:  2.30E+4nMAssay Description:Inhibitory activity against thrombin(fIIa) in human plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed