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BDBM50102018 3-(4-Piperidin-1-yl-cyclohex-1-enyl)-1H-indole-5-carbonitrile::CHEMBL298733

SMILES: N#Cc1ccc2[nH]cc(C3=CCC(CC3)N3CCCCC3)c2c1

InChI Key: InChIKey=YHEDKBGNEHMPML-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50102018   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))
BDBM50102018
PNG
(3-(4-Piperidin-1-yl-cyclohex-1-enyl)-1H-indole-5-c...)
Show SMILES N#Cc1ccc2[nH]cc(C3=CCC(CC3)N3CCCCC3)c2c1
Show InChI InChI=1S/C20H23N3/c21-13-15-4-9-20-18(12-15)19(14-22-20)16-5-7-17(8-6-16)23-10-2-1-3-11-23/h4-5,9,12,14,17,22H,1-3,6-8,10-11H2
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
178n/an/an/an/an/an/an/an/a



Wyeth-Ayerst Research Laboratories

Curated by ChEMBL


Assay Description
In vitro for its binding affinity for serotonin transporter RB5-HT-T in rat cortical membranes


Bioorg Med Chem Lett 11: 1885-8 (2001)


Article DOI: 10.1016/s0960-894x(01)00334-1
BindingDB Entry DOI: 10.7270/Q2GM86K9
More data for this
Ligand-Target Pair