BDBM50102768 2-(2-Hydroxy-phenyl)-1H-indole-5-carboxamidine::CHEMBL284805
SMILES NC(=N)c1ccc2[nH]c(cc2c1)-c1ccccc1O
InChI Key InChIKey=JPGNPKIYCTXJPG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 16 hits for monomerid = 50102768
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals
Curated by ChEMBL
Axys Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.40E+3nMAssay Description:Inhibitory concentration against Human Serine Protease Urokinase Plasminogen ActivatorMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals
Curated by ChEMBL
Axys Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.40E+3nMAssay Description:Inhibition of human uPA by fluorescence based assay using L-PyroGlu-Gly-Arg-pNA.HCl as substrateMore data for this Ligand-Target Pair
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals
Curated by ChEMBL
Axys Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.40E+3nMAssay Description:Inhibition of urokinase-type plasminogen activator (microPa)More data for this Ligand-Target Pair
Affinity DataKi: 2.70E+3nMAssay Description:Inhibition of human factor 10a by fluorescence based assay using CH3OCO-D-CHA-Gly-Arg-pNA.AcoH as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 2.70E+3nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
Affinity DataKi: 8.00E+3nMAssay Description:Activity against Human Serine Protease TrypsinMore data for this Ligand-Target Pair
Affinity DataKi: 8.00E+3nMAssay Description:Inhibition of human trypsin by fluorescence based assay using 25 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 9.40E+3nMAssay Description:Inihibtion of Human Serine Protease tissue type Plasminogen ActivatorMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nMAssay Description:Inhibition of human plasmin by fluorescence based assay using pyroGlu-Phe-Lys-pNA.HCl as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 1.20E+4nMAssay Description:Inhibition of Human Serine Protease PlasminMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+4nMAssay Description:Activity against Human Serine Protease ThrombinMore data for this Ligand-Target Pair
Affinity DataKi: 1.30E+4nMAssay Description:Inhibition of human thrombin by fluorescence based assay using 100 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
Affinity DataKi: 3.50E+4nMAssay Description:Inhibition of human recombinant hepsin by fluorescence based assay using 65 uM BOC-Gln-Arg-Arg -AMC as substrateMore data for this Ligand-Target Pair
TargetSuppressor of tumorigenicity 14 protein(Homo sapiens (Human))
Aurigene Discovery Technologies
Curated by ChEMBL
Aurigene Discovery Technologies
Curated by ChEMBL
Affinity DataKi: 6.00E+4nMAssay Description:Inhibition of human recombinant matriptase by fluorescence based assay using 20 uM Boc-Gln-Ala-Arg-7-amido-4-methyl coumarinhydrobromide as substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of recombinant human hepsin using Boc-QAR-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+4nMAssay Description:Compound was evaluated for inhibition of human alpha-thrombin catalytic activity.More data for this Ligand-Target Pair