BDBM50102771 2-(3-Fluoro-2-hydroxy-phenyl)-1H-benzoimidazole-5-carboxamidine::CHEMBL96494

SMILES NC(=N)c1ccc2nc([nH]c2c1)-c1cccc(F)c1O

InChI Key InChIKey=PJDBBQFSBXNSTE-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50102771   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102771(2-(3-Fluoro-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  550nMAssay Description:ComInhibition of Human Serine Protease Urokinase Plasminogen Activator (u-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102771(2-(3-Fluoro-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  890nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102771(2-(3-Fluoro-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of Human Serine Protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102771(2-(3-Fluoro-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  5.50E+3nMAssay Description:Inhibition of Human Serine Protease Plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102771(2-(3-Fluoro-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of Human Serine Protease Thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102771(2-(3-Fluoro-2-hydroxy-phenyl)-1H-benzoimidazole-5-...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of Human Serine Protease tissue type Plasminogen Activator (t-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed