BDBM50102783 2-(1-Hydroxy-naphthalen-2-yl)-1H-benzoimidazole-5-carboxamidine::CHEMBL319997

SMILES NC(=N)c1ccc2nc([nH]c2c1)-c1ccc2ccccc2c1O

InChI Key InChIKey=JGJHMYSBPBDONZ-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50102783   

TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102783(2-(1-Hydroxy-naphthalen-2-yl)-1H-benzoimidazole-5-...)
Affinity DataKi:  3.90E+3nMAssay Description:ComInhibition of Human Serine Protease Urokinase Plasminogen Activator (u-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102783(2-(1-Hydroxy-naphthalen-2-yl)-1H-benzoimidazole-5-...)
Affinity DataKi:  9.90E+3nMAssay Description:Binding affinity against human coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102783(2-(1-Hydroxy-naphthalen-2-yl)-1H-benzoimidazole-5-...)
Affinity DataKi:  1.80E+4nMAssay Description:Inhibition of Human Serine Protease Trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102783(2-(1-Hydroxy-naphthalen-2-yl)-1H-benzoimidazole-5-...)
Affinity DataKi:  3.10E+4nMAssay Description:Inhibition of Human Serine Protease tissue type Plasminogen Activator (t-PA).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102783(2-(1-Hydroxy-naphthalen-2-yl)-1H-benzoimidazole-5-...)
Affinity DataKi:  3.30E+4nMAssay Description:Inhibition of Human Serine Protease Plasmin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Axys Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50102783(2-(1-Hydroxy-naphthalen-2-yl)-1H-benzoimidazole-5-...)
Affinity DataKi:  8.00E+4nMAssay Description:Inhibition of Human Serine Protease Thrombin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed