BDBM50103023 (S)-5-Guanidino-2-((S)-3-(4-methoxy-phenyl)-2-{3-[3-piperidin-1-ylmethyl-1-(4-trifluoromethoxy-benzyl)-1H-indol-6-yl]-ureido}-propionylamino)-pentanoic acid cyclohexylmethyl-amide::CHEMBL302603

SMILES COc1ccc(C[C@H](NC(=O)Nc2ccc3c(CN4CCCCC4)cn(Cc4ccc(OC(F)(F)F)cc4)c3c2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC2CCCCC2)cc1

InChI Key InChIKey=PSQPTKLJJATCRJ-ZAQUEYBZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50103023   

TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103023((S)-5-Guanidino-2-((S)-3-(4-methoxy-phenyl)-2-{3-[...)
Affinity DataIC50:  5.60E+3nMAssay Description:In vitro displacement of [3H]-S-(p-F-Phe)-homoarginine-K Y-NH2 (at a concentration of 10 microM) from thrombin receptor (PAR-1) on the membranes of C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103023((S)-5-Guanidino-2-((S)-3-(4-methoxy-phenyl)-2-{3-[...)
Affinity DataIC50:  3.65E+4nMAssay Description:In vitro displacement of [3H]-S-(p-F-Phe)-homoarginine-K Y-NH2 (at a concentration of 10 microM) from thrombin receptor (PAR-1) on the membranes of C...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteinase-activated receptor 1(Homo sapiens (Human))
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50103023((S)-5-Guanidino-2-((S)-3-(4-methoxy-phenyl)-2-{3-[...)
Affinity DataIC50:  5.60E+3nMAssay Description:In vitro inhibition of human platelet aggregation induced by alpha-thrombin (at a concentration of 0.15 nM)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed