BDBM50103964 CHEMBL3593932

SMILES [O-][N+](=O)c1ccc(\C=C\C=C2/C(=O)N(Cc3ccc(OCCF)cc3)c3ccccc23)cc1

InChI Key InChIKey=AOIUAVCQCDCNFO-YVCQAPTRSA-N

Data  3 KI  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50103964   

TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50103964(CHEMBL3593932)
Affinity DataKi:  2.10nMAssay Description:Displacement of Thio-T from recombinant alpha-synuclein (unknown origin) expressed in Escherichia coli after 1.5 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50103964(CHEMBL3593932)
Affinity DataKi:  80nMAssay Description:Displacement of Thio-T from human recombinant tau (243 to 375) expressed in Escherichia coli BL21(DE3)RIL after 1.5 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50103964(CHEMBL3593932)
Affinity DataKi:  142nMAssay Description:Displacement of Thio-T from amyloid beta (1 to 42) (unknown origin) expressed in Escherichia coli after 1.5 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50103964(CHEMBL3593932)
Affinity DataKd:  50nMAssay Description:Binding affinity human recombinant tau (243 to 375) expressed in Escherichia coli BL21(DE3)RIL after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50103964(CHEMBL3593932)
Affinity DataKd:  271nMAssay Description:Binding affinity amyloid beta (1 to 42) (unknown origin) expressed in Escherichia coli after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL
LigandPNGBDBM50103964(CHEMBL3593932)
Affinity DataKd:  8.90nMAssay Description:Binding affinity to recombinant alpha-synuclein (unknown origin) expressed in Escherichia coli after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed