BDBM50104356 4-[5-(4-Fluoro-phenyl)-2-phenyl-3H-imidazol-4-yl]-pyridine::CHEMBL416169

SMILES Fc1ccc(cc1)-c1[nH]c(nc1-c1ccncc1)-c1ccccc1

InChI Key InChIKey=AZBHFSLUTGHEPH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50104356   

TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104356(4-[5-(4-Fluoro-phenyl)-2-phenyl-3H-imidazol-4-yl]-...)
Affinity DataIC50: >2.00E+4nMAssay Description:Binding affinity towards human glucagon receptor in absence of Mg2+ expressed as IC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104356(4-[5-(4-Fluoro-phenyl)-2-phenyl-3H-imidazol-4-yl]-...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human glucagon receptor expressed in CHO cell membranes by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50104356(4-[5-(4-Fluoro-phenyl)-2-phenyl-3H-imidazol-4-yl]-...)
Affinity DataIC50:  130nMAssay Description:Binding affinity towards human Mitogen-activated protein kinase p38 expressed as IC50More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50104356(4-[5-(4-Fluoro-phenyl)-2-phenyl-3H-imidazol-4-yl]-...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against interleukin-1(IL-1) synthesis, using intact human monocytesMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University Of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50104356(4-[5-(4-Fluoro-phenyl)-2-phenyl-3H-imidazol-4-yl]-...)
Affinity DataIC50:  154nMAssay Description:Inhibition of p38alpha MAPKMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed