BDBM50104853 CHEMBL110578::N-[2-(2,5-Dichloro-phenyl)-cyclopropanecarbonyl]-guanidine

SMILES NC(=N)NC(=O)[C@H]1C[C@@H]1c1cc(Cl)ccc1Cl

InChI Key InChIKey=NINVLLPACOWOFH-SVRRBLITSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50104853   

TargetSodium/hydrogen exchanger 1(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104853(CHEMBL110578 | N-[2-(2,5-Dichloro-phenyl)-cyclopro...)
Affinity DataIC50:  40nMAssay Description:Screened in AP1 cells expressing human NHE-1 for sodium hydrogen exchange activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed