BDBM50104968 CHEMBL114804::N*4*-Hydroxy-N*1*-(2-hydroxy-indan-1-yl)-2-(4-methoxy-benzyl)-succinamide

SMILES COc1ccc(C[C@H](CC(=O)NO)C(=O)N[C@@H]2[C@H](O)Cc3ccccc23)cc1

InChI Key InChIKey=VUKNURXXGDIFMO-ZTNFWEORSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50104968   

TargetNeutrophil collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104968(CHEMBL114804 | N*4*-Hydroxy-N*1*-(2-hydroxy-indan-...)
Affinity DataKi:  9.20nMAssay Description:Inhibition of matrix metalloprotease-8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104968(CHEMBL114804 | N*4*-Hydroxy-N*1*-(2-hydroxy-indan-...)
Affinity DataKi:  52nMAssay Description:Inhibition of matrix metalloprotease-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104968(CHEMBL114804 | N*4*-Hydroxy-N*1*-(2-hydroxy-indan-...)
Affinity DataKi:  203nMAssay Description:Inhibition of human matrix metalloprotease-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Dupont Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50104968(CHEMBL114804 | N*4*-Hydroxy-N*1*-(2-hydroxy-indan-...)
Affinity DataKi:  1.16E+3nMAssay Description:Inhibition of matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed