BDBM50105206 4-(4-Acetylamino-phenoxy)-thieno[2,3-c]pyridine-2-carboxylic acid amide::CHEMBL434222

SMILES CC(=O)Nc1ccc(Oc2cncc3sc(cc23)C(N)=O)cc1

InChI Key InChIKey=HTOZHWWXFWCYGA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50105206   

TargetVascular cell adhesion protein 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105206(4-(4-Acetylamino-phenoxy)-thieno[2,3-c]pyridine-2-...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of VCAM-1 in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50105206(4-(4-Acetylamino-phenoxy)-thieno[2,3-c]pyridine-2-...)
Affinity DataIC50:  29nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntercellular adhesion molecule 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105206(4-(4-Acetylamino-phenoxy)-thieno[2,3-c]pyridine-2-...)
Affinity DataIC50:  150nMAssay Description:Inhibition of intercellular adhesion molecule-1 (ICAM1) in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE-selectin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50105206(4-(4-Acetylamino-phenoxy)-thieno[2,3-c]pyridine-2-...)
Affinity DataIC50:  380nMAssay Description:Inhibition of selectin E in human endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed